Researchers at the Mayo Clinic have identified two factors independently associated with shorter progression-free survival (PFS) in patients with grade 4 isocitrate dehydrogenase (IDH)-mutant astrocytoma: cyclin-dependent kinase inhibitor 2A/B (CDKN2A/B) deletion and midline tumour involvement. The findings, published in Neurology,

A research team at Hannover Medical School (MHH) in Germany has uncovered new insights into the long-term survival of kidney transplants. Led by Professor Christian Hinze, the study identified specific properties of kidney cells that can indicate how well a

Researchers at the University of Edinburgh have developed a comprehensive map detailing how hundreds of mutations in a critical cancer gene influence tumour development. The study, published in Nature Genetics, focused on CTNNB1, a gene responsible for producing β-catenin, a